EMD-80135

Single-particle
3.1 Å
EMD-80135
3D View Gallery
Deposition: 06/04/2026
Map released: 20/05/2026
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80135

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-25ij summary report (pdf.gz) Map-25ij FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human Nav1.6 in complex with delta-paraponeritoxin-Pc1a

EMD-80135

Single-particle
3.1 Å
EMD-80135
3D View Gallery
Deposition: 06/04/2026
Map released: 20/05/2026
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Paraponera clavata
Sample: Nav1.6-Pc1a
Fitted models: 25ij

Deposition Authors: Yang L, Fan X, Huang J, Yan N
Diverse binding poses of agonistic neurotoxins on human Na v 1.6.
Fan X, Huang J, Yang L, Chen J, Wang H, Huang X, Geng J, Wu Q, Xie Y, Lu F, Guo Q, Shen Z, Jin X, Yan N
(2026) Nature , 656 , 250 - 259
PUBMED: 42271061
DOI: doi:10.1038/s41586-026-10661-x
ISSN: 1476-4687
ASTM: NATUAS