EMDB EMD-7968

Single particle reconstruction
3.6Å resolution

Cryo-EM structure of human Ptch1 and ShhN complex

Map released:
Overview of EMD-7968
Source organism: Homo sapiens [9606]
Fitted atomic model: 6dmy
Related EM entry by publication: EMD-7963, EMD-7964
Primary publication:
Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N
Science - (2018)
PMID: 29954986

Function and Biology Details

Sample name: Patch1
Cellular component: Patch1
Ligands: N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL HEMISUCCINATE, SERINE, ZINC ION, CALCIUM ION
Proteins: Protein patched homolog 1, Sonic hedgehog protein

Experimental Information Details

Resolution: 3.6Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)