EMDB EMD-7901

Single particle reconstruction
19.0Å resolution

REGN3470 antibody Fab in complex with Ebola virus GP

Map released:
Overview of EMD-7901
Source organism: Ebola virus - Mayinga, Zaire, 1976 [128952]
Related EM entry by publication: EMD-7900, EMD-7902
Primary publication:
Development of clinical-stage human monoclonal antibodies that treat advanced Ebola virus disease in non-human primates.
Pascal KE, Dudgeon D, Trefry JC, Anantpadma M, Sakurai Y, Murin CD, Turner HL, Fairhurst J, Torres M, Rafique A, Yan Y, Badithe A, Yu K, Potocky T, Bixler SL, Chance TB, Pratt WD, Rossi FD, Shamblin JD, Wollen SE, Zelko JM, Carrion R, Worwa G, Staples HM, Burakov D, Babb R, Chen G, Martin J, Huang TT, Erlandson K, Willis MS, Armstrong K, Dreier TM, Ward AB, Davey RA, Pitt MLM, Lipsich L, Mason P, Olson W, Stahl N, Kyratsous CA
J. Infect. Dis. - (2018)
PMID: 29860496

Function and Biology Details

Sample name: REGN3470 antibody Fab in complex with Ebola virus GP
Protein: REGN3470 antibody Fab in complex with Ebola virus GP

Experimental Information Details

Resolution: 19.0Å
Resolution method: FSC 0.5 CUT-OFF
Applied symmetry: C3
Reconstruction software: EMAN2
Microscope: FEI TECNAI SPIRIT
Detector: TVIPS TEMCAM-F416 (4k x 4k)