EMDB EMD-7882

Single particle reconstruction
3.32Å resolution

Full-length 5-HT3A receptor in a serotonin-bound conformation- State 1

Map released:
Overview of EMD-7882
Source organism: Mus musculus [10090]
Fitted atomic model: 6dg7
Related EM entry by publication: EMD-7883
Primary publication:
Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3A receptor
Basak S, Gicheru Y, Rao S, Sansom MSP, Chakrapani S
Nature - (2018)

Function and Biology Details

Sample name: Serotonin receptor
Cellular component: Serotonin receptor
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, SEROTONIN, water
Protein: 5-hydroxytryptamine receptor 3A

Experimental Information Details

Resolution: 3.32Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C5
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)