EMDB EMD-7876

Single particle reconstruction
3.85Å resolution

BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding

Map released:
Last modified:
Overview of EMD-7876
Source organisms:
Fitted atomic model: 6dfh
Related EM entries by publication: EMD-7875, EMD-7884, EMD-7885
Primary publication:
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, Hu X, Bernard SM, Georgeson E, Phelps N, Adachi Y, Kubitz M, Landais E, Umotoy J, Robinson A, Briney B, Wilson IA, Burton DR, Ward AB, Crotty S, Batista FD, Schief WR
Science - (2019)
PMID: 31672916

Function and Biology Details

Sample name: BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE
Proteins: BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding, SOSIP trimer, BG18 fragment antigen, Envelope glycoprotein gp160, Envelope glycoprotein gp160, germline-reverted BG18 fragment antigen binding heavy chain, germline-reverted BG18 fragment antigen binding light chain

Experimental Information Details

Resolution: 3.85Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)