EMDB EMD-7822

Single particle reconstruction
3.8Å resolution

Cryo-EM structure of the zebrafish TRPM2 channel in the presence of Ca2+

Map released:
Last modified:
Overview of EMD-7822
Source organism: Danio rerio [7955]
Fitted atomic model: 6d73
Related EM entries by publication: EMD-20367, EMD-20368, EMD-20369
Primary publication:
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun 10 3740-3740 (2019)
PMID: 31431622

Function and Biology Details

Sample name: Transient receptor potential cation channel subfamily M member 2 (TRPM2)
Ligand: CALCIUM ION
Proteins: Transient receptor potential cation channel subfamily M member 2 (TRPM2), Transient receptor potential cation channel, subfamily M

Experimental Information Details

Resolution: 3.8Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C2
Reconstruction software: RELION
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)