EMD-76733

Single-particle
3.38 Å
EMD-76733
3D View Gallery
Deposition: 16/04/2026
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76733

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12sn summary report (pdf.gz) Map-12sn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SARS-CoV-2 RNA-dependent RNA polymerase in complex with 4'-FlA nucleotide analogue

EMD-76733

Single-particle
3.38 Å
EMD-76733
3D View Gallery
Deposition: 16/04/2026
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 RNA-dependent RNA polymerase in complex with 4'-FlA nucleotide analogue
Fitted models: 12sn

Deposition Authors: Park S, Gharpure A, Ward AB
Substrate and target selectivity of 4'-fluoroadenosine against viral and host polymerases.
Walker SM , Loutan AJ, Tchesnokov EP , Kocincova D, Gordon CJ , Escobedo RA, Jackson N, Vogel OA , Morsheimer K, Park S, Gharpure A, Urbano I, Heacock M, Cheng Z, Pathak K, Wolff KC, Huerta L, Bakowski MA, Riva L, Gupta AK, Yu C, Das K, Martinez-Sobrido L, Basler CF, Davey R, Wilson IA, Ward AB , Chanda S , Chatterjee AK, Gotte M
(2026) bioRxiv
PUBMED: 42244653
DOI: doi:10.64898/2026.05.22.727251
ISSN: 2692-8205