EMDB EMD-7621

Single particle reconstruction
4.0Å resolution

Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody vFP7.04 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122

Map released:
Last modified:
Overview of EMD-7621
Source organisms:
Fitted atomic model: 6cue
Primary publication:
Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
Dingens AS, Acharya P, Haddox HK, Rawi R, Xu K, Chuang GY, Wei H, Zhang B, Mascola JR, Carragher B, Potter CS, Overbaugh J, Kwong PD, Bloom JD
PLoS Pathog. 14 e1007159-e1007159 (2018)
PMID: 29975771

Function and Biology Details

Sample name: vFP7.04-BG505 DS-SOSIP-VRC03-PGT122
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE
Proteins: vFP7.04-BG505 DS-SOSIP-VRC03-PGT122, PGT122, VRC03, Glycoprotein, vFP7.04, Envelope glycoprotein gp120, Envelope glycoprotein gp41, vFP7.04 Heavy chain, vFP7.04 light chain, PGT122 heavy Chain, PGT122 Light chain, VRC03 Heavy chain, VRC03 light chain

Experimental Information Details

Resolution: 4.0Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)