EMDB EMD-7620

Single particle reconstruction
3.3Å resolution

Structure of the human TRPC3 in a lipid-occupied, closed state

Map released:
Last modified:
Overview of EMD-7620
Source organism: Homo sapiens [9606]
Fitted atomic model: 6cud
Primary publication:
Structure of the human lipid-gated cation channel TRPC3.
Fan C, Choi W, Sun W, Du J, Lu W
Elife 7 - (2018)
PMID: 29726814

Function and Biology Details

Sample name: TRPC3
Ligands: (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (2R)-3-hydroxypropane-1,2-diyl dihexanoate, N-ACETYL-D-GLUCOSAMINE
Proteins: TRPC3, Short transient receptor potential channel 3

Experimental Information Details

Resolution: 3.3Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Reconstruction software: FREALIGN
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)