EMD-75618

Single-particle
2.1 Å
EMD-75618
3D View Gallery
Deposition: 17/02/2026
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75618

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-11cl summary report (pdf.gz) Map-11cl FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human TRPV1 in complex with Asivatrep

EMD-75618

Single-particle
2.1 Å
EMD-75618
3D View Gallery
Deposition: 17/02/2026
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tetrameric hTRPV1 in complex with Asivatrep
Fitted models: 11cl

Deposition Authors: Lopez KE, Van Horn WD
TRPV1 antagonism occurs through diverse structural mechanisms.
Lopez KE, Paduda AS, Derrick MJ, Van Horn WD
(2026) bioRxiv
PUBMED: 42094379
DOI: doi:10.64898/2026.04.27.721197
ISSN: 2692-8205