EMDB EMD-7542

Single particle reconstruction
3.07Å resolution

Structure of the nvTRPM2 channel in complex with Ca2+

Map released:
Last modified:
Overview of EMD-7542
Source organism: Nematostella vectensis [45351]
Fitted atomic model: 6co7
Primary publication:
Structure of a TRPM2 channel in complex with Ca2+explains unique gating regulation.
Zhang Z, Toth B, Szollosi A, Chen J, Csanady L
Elife 7 - (2018)
PMID: 29745897

Function and Biology Details

Sample name: nvTRPM2 tetramer
Ligands: N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, SODIUM ION
Proteins: nvTRPM2 tetramer, Predicted protein

Experimental Information Details

Resolution: 3.07Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)