EMD-75247

Tomography
EMD-75247 Deposition: 23/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75247

Cryo-tomogram of a matured NLRP3 inflammasome condensate at the MTOC

EMD-75247

Tomography
EMD-75247 Deposition: 23/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview Sample Experiment Validation Additional data Links
Sample Organism: Human THP-1 cells
Sample: Differentiated human THP-1 cells treated with LPS, followed by 30 min of nigericin

Deposition Authors: Wang J , Wu M, Xiao L, Du G, Chen M , Magupalli VG, Dahlberg PD , Wu H , Jensen GJ

Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center