EMD-75245

Tomography
EMD-75245
Gallery
Deposition: 23/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75245
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Cryo-tomogram of a solid-like NLRP3 inflammasome condensate at the MTOC

EMD-75245

Tomography
EMD-75245
Gallery
Deposition: 23/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview Sample Experiment Validation Additional data Links
Sample Organism: Human THP-1 cells
Sample: Differentiated human THP-1 cells treated with LPS, followed by 10 min of nigericin

Deposition Authors: Wang J , Wu M, Xiao L, Du G, Chen M , Magupalli VG, Dahlberg PD , Wu H , Jensen GJ

Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center
Wang J , Man W, Xiao L, Du G, Chen M , Magupalli VG, Dahlberg PD , Wu H , Jensen GJ
To Be Published