EMD-75233
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (global refinement)
EMD-75233
Single-particle3.8 Å
Deposition: 23/01/2026Map released: 13/05/2026
Last modified: 03/06/2026
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2,
SARS-CoV-2 pseudovirus
Sample: VN01H1 Fab-bound SARS-CoV-2 E-FIC
Deposition Authors: Park YJ
,
Seattle Structural Genomics Center for Infectious Disease (SSGCID),
Veesler D
Sample: VN01H1 Fab-bound SARS-CoV-2 E-FIC
Deposition Authors: Park YJ
,
Seattle Structural Genomics Center for Infectious Disease (SSGCID),
Veesler D
TMPRSS2-mediated coronavirus spike activation and inhibition.
McCallum M ,
Case JB ,
Brown JT,
Park YJ ,
Lee J,
Sutherland E ,
Aggarwal A,
Gibson C,
Lempp FA ,
Stewart C ,
Tortorici MA ,
Sanapala S,
Low JS,
Asarnow D ,
Bohan D ,
Dellota Jr E,
Merz B,
Chawla B,
Kar S,
Lanzavecchia A ,
Sallusto F,
Riley NM ,
Turville S,
Purcell L,
Diamond MS ,
Veesler D
(2026) Nat Struct Mol Biol , 33 , 810 - 823
,
Case JB ,
Brown JT,
Park YJ ,
Lee J,
Sutherland E ,
Aggarwal A,
Gibson C,
Lempp FA ,
Stewart C ,
Tortorici MA ,
Sanapala S,
Low JS,
Asarnow D ,
Bohan D ,
Dellota Jr E,
Merz B,
Chawla B,
Kar S,
Lanzavecchia A ,
Sallusto F,
Riley NM ,
Turville S,
Purcell L,
Diamond MS ,
Veesler D
(2026) Nat Struct Mol Biol , 33 , 810 - 823
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