EMD-75142

Single-particle
3.21 Å
EMD-75142
3D View Gallery
Deposition: 17/01/2026
Map released: 25/02/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75142

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-10ft summary report (pdf.gz) Map-10ft FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of receptor tyrosine kinase ROS1 in complex with NELL2

EMD-75142

Single-particle
3.21 Å
EMD-75142
3D View Gallery
Deposition: 17/01/2026
Map released: 25/02/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Receptor tyrosine kinase ROS1 in complex with NELL2
Fitted models: 10ft

Deposition Authors: Li H, Klein D
Clustering and a conformational switch drive activation of the mammalian receptor tyrosine kinase ROS1.
Li H, Zhang J, Li T , Wang Y, Alarcon CR , Klein DE
(2026) Nat Commun , 17
PUBMED: 41698918
DOI: doi:10.1038/s41467-026-69630-7
ISSN: 2041-1723