EMDB < EMD-74809

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

EMD-74809

Single-particle
15.17 Å

EMD-74809

3D View Gallery

Deposition: 23/12/2025
Map released: 14/01/2026
Last modified: 14/01/2026

Overview 3D View Sample Experiment Validation Additional data Links

Overview 3D View Sample Experiment Validation Additional data Links

EMD-74809

Download

HCV Chiron E1E2 complexed with AR3A and AR4A Fabs

EMD-74809

Single-particle
15.17 Å
EMD-74809

EMD-74809

3D View Gallery

Deposition: 23/12/2025
Map released: 14/01/2026
Last modified: 14/01/2026

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Hepacivirus hominis
Sample: HCV Chiron E1E2 complexed with AR3A and AR4A Fabs

Deposition Authors: Hung S-H, Law M

Antigenic and EM characterization of the Chiron experimental hepatitis C virus vaccine.

Hung SH, Torres JL, Chen F, Giang E, Ward AB, Law M
(2025) Vaccine , 58 , 127239

PUBMED: 40381513
DOI: doi:10.1371/journal.ppat.1006214
ISSN: 1873-2518

Grant Support:

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI158193 (United States)
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI168251 (United States)