EMD-74629

Single-particle
3.4 Å
EMD-74629
3D View Gallery
Deposition: 20/12/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74629

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zrs summary report (pdf.gz) Map-9zrs FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Shigella flexneri type III secretion system (T3SS) protein IpaD bound to hemolysis blocking Fab D02-F2 and hemolysis enhancing Fab D02-E4

EMD-74629

Single-particle
3.4 Å
EMD-74629
3D View Gallery
Deposition: 20/12/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Macaca mulatta, Shigella flexneri
Sample: Shigella flexneri type III secretion system (T3SS) protein IpaD bound to hemolysis blocking Fab D02-F2 and hemolysis enhancing Fab D02-E4, both stablized by an anti-Fab nanobody.
Fitted models: 9zrs

Deposition Authors: Gilman MSA, Kruse AC, Schmidt HR
Multifunctional antibody responses from a primate Shigella outbreak inform vaccine design.
Gallant RM, Savarino P, Pulido S, Gilman MSA, Lu T, Hayes J, Xerri NL, Williams T, Ochoa MA, Dietz Z, Peterson E, Scott T, Hartmann F, Baker SG, Kaminski RW, Sok D, Kruse AC, Picking W, Capuano SV, Schmidt HR
(2026) Sci Transl Med , 18 , eaef7084 - eaef7084
PUBMED: 42685149
DOI: doi:10.1126/scitranslmed.aef7084
ISSN: 1946-6242