EMDB EMD-7457

Single particle reconstruction
3.73Å resolution

Structure of the HIV-Nef bound AP-1:Arf1 closed trimer monomeric subunit

Map released:
Last modified:
Overview of EMD-7457
Source organism: Homo sapiens [9606]
Fitted atomic model: 6cm9
Related EM entries by publication: EMD-7453, EMD-7454, EMD-7455, EMD-7456, EMD-7458, EMD-7563
Primary publication:
HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Morris KL, Buffalo CZ, Sturzel CM, Heusinger E, Kirchhoff F, Ren X, Hurley JH
Cell 174 659-671.e14 (2018)
PMID: 30053425

Function and Biology Details

Sample name: Closed trimer assembly of AP-1:Arf1:Tetherin-Nef
Protein: Closed trimer assembly of AP-1:Arf1:Tetherin-Nef

Experimental Information Details

Resolution: 3.73Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)