EMD-74451

Composite map
Single-particle
2.9 Å
EMD-74451
3D View Gallery
Deposition: 14/12/2025
Map released: 04/02/2026
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74451
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9znn summary report (pdf.gz) Map and 9znn FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) in complex with APPB, composite map

EMD-74451

Composite map
Single-particle
2.9 Å
EMD-74451
3D View Gallery
Deposition: 14/12/2025
Map released: 04/02/2026
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) in complex with APPB
Fitted models: 9znn

Deposition Authors: Kirsh JM, Ochoa JM, Soroush-Pejrimovsky MT, Kaudeer BY, Clemons WM
Structures of bacterial and human phosphoglycosyltransferases bound to a common inhibitor inform selective therapeutics.
Kaudeer BY, Kirsh JM, Mitachi K, Ochoa JM, Soroush-Pejrimovsky MT, Li YE, Nguyen VN, Kurosu M, Clemons Jr WM
(2025) bioRxiv
PUBMED: 41446129
DOI: doi:10.64898/2025.12.16.694696
ISSN: 2692-8205