EMDB EMD-7444

Single particle reconstruction
3.0Å resolution

Electron cryo-microscopy of the eukaryotic translation initiation factor 2B from Homo sapiens

Map released:
Overview of EMD-7444
Source organism: Homo sapiens [9606]
Related EM entry by publication: EMD-7442, EMD-7443
Primary publication:
Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule.
Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P
Science 359 - (2018)
PMID: 29599213

Function and Biology Details

Sample name: Translation initiation factor eIF-2B decamer
Protein: Translation initiation factor eIF-2B decamer

Experimental Information Details

Resolution: 3.0Å
Resolution method: FSC 0.5 CUT-OFF
Applied symmetry: C2
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)