EMD-74378

Single-particle
2.8 Å
EMD-74378
3D View Gallery
Deposition: 07/12/2025
Map released: 29/04/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74378

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zkn summary report (pdf.gz) Map-9zkn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The TMD structure of native mouse AMPAR with 4 TARPs

EMD-74378

Single-particle
2.8 Å
EMD-74378
3D View Gallery
Deposition: 07/12/2025
Map released: 29/04/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: native AMPAR
Fitted models: 9zkn

Deposition Authors: Fang CL , Gouaux E
Native AMPA receptor architecture reveals SynDIG4 engagement and auxiliary subunit heterogeneity.
Fang C, Gouaux E
(2026) Sci Adv , 12 , eaee7973 - eaee7973
PUBMED: 42284406
DOI: doi:10.1126/sciadv.aee7973
ISSN: 2375-2548
Grant Support: