EMD-74090

Single-particle
3.93 Å
EMD-74090
3D View Gallery
Deposition: 27/11/2025
Map released: 15/04/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74090
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ze3 summary report (pdf.gz) Map and 9ze3 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the endogenous U2/branchpoint spliceosomal complex (Distal DHX15 state)

EMD-74090

Single-particle
3.93 Å
EMD-74090
3D View Gallery
Deposition: 27/11/2025
Map released: 15/04/2026
Last modified: 15/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Endogenous U2/branchpoint spliceosomal complex (Distal DHX15)
Fitted models: 9ze3

Deposition Authors: Liu S, Su T, Zhou ZH
The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing.
Liu S, Su T, Huang J, Lin CH, Black DL, Damianov A, Zhou ZH
(2026) bioRxiv
PUBMED: 41929118
DOI: doi:10.64898/2026.03.26.714623
ISSN: 2692-8205