EMD-74041

Single-particle
2.86 Å
EMD-74041
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Deposition: 24/11/2025
Map released: 25/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74041
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9zcu summary report (pdf.gz) Map and 9zcu FULL report (pdf.gz)
EMICSS annotations (xml)

Human TRPM8 V915Y fully-swapped, closed, ligand-free structure resolved in GDN

EMD-74041

Single-particle
2.86 Å
EMD-74041
3D View Gallery
Deposition: 24/11/2025
Map released: 25/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotetrameric complex of human TRPM8 V915Y determined in a cell-derived vesicles.
Fitted models: 9zcu

Deposition Authors: Choi KY, Lin X, Cheng Y, Julius D
Structural energetics of cold sensitivity
Choi KY, Lin X, Cheng Y, Julius D
(2026) Nature
DOI: doi:10.1038/s41586-026-10276-2
ISSN: 1476-4687
ASTM: NATUAS