EMD-73949
Q23.MD39 in Complex with Fabs from antibodies CH01 and 35O22
EMD-73949
Single-particle3.49 Å
Deposition: 18/11/2025Map released: 22/04/2026
Last modified: 13/05/2026
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: Q23.MD39 Env trimer in Complex with CH01 and 35O22
Fitted models: 9z9l
Deposition Authors: Lin ZJ, Cui J, Du J, Habib R, Kulp D, Pallesen J
Sample: Q23.MD39 Env trimer in Complex with CH01 and 35O22
Fitted models: 9z9l
Deposition Authors: Lin ZJ, Cui J, Du J, Habib R, Kulp D, Pallesen J
Deep mining of the human antibody repertoire identifies frequent and genetically diverse CDRH3 topologies targetable by vaccination.
Habib R,
Solieva SO ,
Lin ZJ,
Ghosh S,
Bayruns K,
Singh M ,
Agostino CJ ,
Tursi NJ,
Sowers KJ ,
Huang J,
Roark RS,
Purwar M,
Park Y,
Ayyanathan K,
Li H,
Carey JW,
Kim A,
Park J,
McCanna ME,
Skelly AN ,
Chokkalingam N,
Kriete S,
Shupin N,
Huynh A,
Walker S ,
Sadeesh R,
Laenger N,
Du J,
Cui J,
Patel A ,
Escolano A,
Kwong PD ,
Shapiro L,
Bowman GR ,
Hahn BH,
Shaw GM,
Weiner DB,
Pallesen J ,
Kulp DW
(2026) PNAS , 123 , e2532810123 - e2532810123
,
Lin ZJ,
Ghosh S,
Bayruns K,
Singh M ,
Agostino CJ ,
Tursi NJ,
Sowers KJ ,
Huang J,
Roark RS,
Purwar M,
Park Y,
Ayyanathan K,
Li H,
Carey JW,
Kim A,
Park J,
McCanna ME,
Skelly AN ,
Chokkalingam N,
Kriete S,
Shupin N,
Huynh A,
Walker S ,
Sadeesh R,
Laenger N,
Du J,
Cui J,
Patel A ,
Escolano A,
Kwong PD ,
Shapiro L,
Bowman GR ,
Hahn BH,
Shaw GM,
Weiner DB,
Pallesen J ,
Kulp DW
(2026) PNAS , 123 , e2532810123 - e2532810123
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