EMD-73821

Single-particle
3.06 Å
EMD-73821
3D View Gallery
Deposition: 12/11/2025
Map released: 17/12/2025
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73821
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9z5q summary report (pdf.gz) Map and 9z5q FULL report (pdf.gz)
EMICSS annotations (xml)

HECT domain of NEDD4-2 complex with a targeted nanobody, nb.C11

EMD-73821

Single-particle
3.06 Å
EMD-73821
3D View Gallery
Deposition: 12/11/2025
Map released: 17/12/2025
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: HECT domain of NEDD4-2
Fitted models: 9z5q

Deposition Authors: Afriyie E , Clarke OB
Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies.
Darko-Boateng A , Afriyie E , Morgenstern TJ, Shanmugam SK , Zou X, Laloudakis YD, Choudhury P, Desai M, Kass RS, Vallese F, Clarke OB , Colecraft HM
(2025) Nat Commun , 17 , 378 - 378
PUBMED: 41353348
DOI: doi:10.1038/s41467-025-67068-x
ISSN: 2041-1723