EMD-73803

Single-particle
2.64 Å
EMD-73803
3D View Gallery
Deposition: 10/11/2025
Map released: 10/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73803

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9z4h summary report (pdf.gz) Map-9z4h FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human Wntless in complex with Wnt5a at 1:1 stoichiometry

EMD-73803

Single-particle
2.64 Å
EMD-73803
3D View Gallery
Deposition: 10/11/2025
Map released: 10/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human Wntless in complex with Wnt5a at 1:1 stoichiometry
Fitted models: 9z4h

Deposition Authors: Ge Y, de Almeida Magalhaes T, Wu H, Wang Z, Salic A, Jiang J, Huang P
Conformational cycling of the Wntless transporter drives trafficking and secretion of Wnt morphogens.
Ge Y, de Almeida Magalhaes T, Wu H, van den Boomen DJH, Nguyen TU, Dou T, Yadav GP, Lee S, Wang Z, Lemoff A, Luo X, Menon SS, Zhang M, Wang J, Jin Z, Jiang J, Salic A, Huang P
(2026) Nat Commun
PUBMED: 42321207
DOI: doi:10.1038/s41467-026-74521-y
ISSN: 2041-1723