EMD-73458

Single-particle
2.5 Å
EMD-73458
3D View Gallery
Deposition: 20/10/2025
Map released: 17/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73458
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ytd summary report (pdf.gz) Map and 9ytd FULL report (pdf.gz)
EMICSS annotations (xml)

Designed antibody vAB66 targeting PAP-HLA A*02:01

EMD-73458

Single-particle
2.5 Å
EMD-73458
3D View Gallery
Deposition: 20/10/2025
Map released: 17/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Lama glama
Sample: vAB-66 Fab bound to HLA-A*02:01 displaying PAP peptide with AD01 nanobofy fiducial
Fitted models: 9ytd

Deposition Authors: Jude KM, Garcia KC
Targeting peptide-MHC complexes with designed T cell receptors and antibodies.
Motmaen A, Jude KM, Wang N, Minervina A, Feldman D, Lichtenstein MA, Ebenezer A, Correnti C, Thomas PG, Garcia KC, Baker D, Bradley P
(2025) bioRxiv
PUBMED: 41332722
DOI: doi:10.1101/2025.11.19.689381
ISSN: 2692-8205