EMD-73283

Single-particle
4.5 Å
EMD-73283
3D View Gallery
Deposition: 13/10/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73283
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9yp4 summary report (pdf.gz) Map and 9yp4 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human beta-cardiac myosin bound to omecamtiv mecarbil in the interacting-heads motif and S2-FH docked state

EMD-73283

Single-particle
4.5 Å
EMD-73283
3D View Gallery
Deposition: 13/10/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens, Aequorea victoria
Sample: Human beta-cardiac myosin bound to omecamtiv mecarbil in the interacting-heads motif and S2-FH docked state
Fitted models: 9yp4

Deposition Authors: Somavarapu AK, Craig R, Padron R

Cryo-EM Reveals How Cardiomyopathy Therapeutic Drugs Modulate the Myosin Motors of the Heart
Somavarapu AK, Ge J, Yengo CM, Craig R, Padron R
To Be Published