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EMD-7311

Single-particle
4.9 Å
EMD-7311
3D View Gallery
Deposition: 20/12/2017
Map released: 31/01/2018
Last modified: 03/02/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-7311
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Structure of PRC2 bound to a H3K27me3/WT hetero-dinucleosome substrate with a 35 bp DNA linker. Masked refinement of PRC2-substrate nucleosome subcomplex.

EMD-7311

Single-particle
4.9 Å
EMD-7311
3D View Gallery
Deposition: 20/12/2017
Map released: 31/01/2018
Last modified: 03/02/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Structure of human PRC2 bound to a hetero-dinucleosome substrate with 35 bp linker DNA. Refinement after signal subtraction to increase resolution of the substrate nucleosome - PRC2 interface.

Deposition Authors: Poepsel S, Kasinath V, Nogales E
Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes.
Poepsel S , Kasinath V, Nogales E
(2018) Nat. Struct. Mol. Biol. , 25 , 154 - 162
PUBMED: 29379173
DOI: doi:10.1038/s41594-018-0023-y
ISSN: 1545-9985