EMDB EMD-7296

Single particle reconstruction
5.7Å resolution

cASIC+mambalgin1 with transmembrane domian

Map released:
Last modified:
Overview of EMD-7296
Source organism: Gallus gallus [9031]
Related EM entry by publication: EMD-6900
Primary publication:
Cryo-EM structure of the ASIC1a-mambalgin-1 complex reveals that the peptide toxin mambalgin-1 inhibits acid-sensing ion channels through an unusual allosteric effect.
Sun D, Yu Y, Xue X, Pan M, Wen M, Li S, Qu Q, Li X, Zhang L, Li X, Liu L, Yang M, Tian C
Cell Discov 4 27-27 (2018)
PMID: 29872539

Function and Biology Details

Sample name: cASIC mambalgin-1
Protein: cASIC mambalgin-1

Experimental Information Details

Resolution: 5.7Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 QUANTUM (4k x 4k)