EMDB EMD-7294

Single particle reconstruction
4.0Å resolution

Cryo-EM Structure of Hepatitis B virus T=4 capsid in complex with the fluorescent allosteric modulator HAP-TAMRA

Map released:
Last modified:
Overview of EMD-7294
Source organism: Hepatitis B virus genotype D subtype adw [10419]
Fitted atomic model: 6bvf
Related EM entry by publication: EMD-7295
Primary publication:
Hepatitis B virus core protein allosteric modulators can distort and disrupt intact capsids.
Schlicksup CJ, Wang JC, Francis S, Venkatakrishnan B, Turner WW, VanNieuwenhze M, Zlotnick A
Elife 7 - (2018)
PMID: 29377794

Function and Biology Details

Sample name: Hepatitis B virus genotype D subtype adw
Ligand: Heteroaryldihydropyrimidine tetramethylrodamine
Protein: Capsid protein
Virus: Hepatitis B virus genotype D subtype adw

Experimental Information Details

Resolution: 4.0Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: I
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)