EMD-72359

Single-particle
3.91 Å
EMD-72359
3D View Gallery
Deposition: 27/08/2025
Map released: 28/01/2026
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72359

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9xzk summary report (pdf.gz) Map-9xzk FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (head structure)

EMD-72359

Single-particle
3.91 Å
EMD-72359
3D View Gallery
Deposition: 27/08/2025
Map released: 28/01/2026
Last modified: 11/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Heterotetrameric SCF-FBH1 protein complex bound to a 3-way DNA fork
Fitted models: 9xzk

Deposition Authors: Mullins EA , Schiltz CJ, Eichman BF
Structural basis for fork reversal and RAD51 regulation by the SCF ubiquitin ligase complex of F-box helicase 1.
Greer BH , Mendia-Garcia J , Mullins EA , Peacock EM , Haigh SK, Schiltz CJ, Aicart-Ramos C , Tsai MS , Cortez D , Moreno-Herrero F , Eichman BF
(2026) Nat Commun , 17
PUBMED: 41587991
DOI: doi:10.1038/s41467-026-68752-2
ISSN: 2041-1723