EMD-72294

Single-particle
4.01 Å
EMD-72294
3D View Gallery
Deposition: 22/08/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72294
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9q7c summary report (pdf.gz) Map and 9q7c FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-electron microscopy structure of PfRIPR bound to monoclonal antibodies RP.092 and RP.052

EMD-72294

Single-particle
4.01 Å
EMD-72294
3D View Gallery
Deposition: 22/08/2025
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Plasmodium falciparum 3D7
Sample: A complex of RH5-interacting protein with monoclonal antibodies
Fitted models: 9q7c

Deposition Authors: Barrett JR, Ward AB
Analysis of monoclonal antibodies against the malaria invasion complex protein RIPR reveals the structural basis for synergistic antibody protection.
Williams BG, Barrett JR, Scott JB, Rigby CA, Cagiada M, Quinkert D, McHugh K, Huhn A, Burnap SA, Gourjault C, Byrne F, Raghavan SSR, Rodrigues A, Bergamaschi L, Balzarotti B, Watson S, Miller N, King LDW, Donnellan FR, Gladstone CA, Paterson J, Scalabrino S, Silk SE, Salkeld J, Minassian AM, Skinner K, Struwe WB, Deane CM, Reece ST, Ward AB, Draper SJ
(2026) Immunity
PUBMED: 42285102
DOI: doi:10.1016/j.immuni.2026.05.012
ISSN: 1074-7613
ASTM: IUNIEH
Grant Support: