EMD-72178
Cereblon Ternary Complex with Blimp1 and compound 5
EMD-72178
Single-particle3.2 Å
Deposition: 15/08/2025Map released: 14/01/2026
Last modified: 14/01/2026
Sample Organism:
Homo sapiens
Sample: Cereblon Ternary Complex with Blimp1 and compound 5
Fitted models: 9q33
Deposition Authors: Watson ER
,
Lander GC
Sample: Cereblon Ternary Complex with Blimp1 and compound 5
Fitted models: 9q33
Deposition Authors: Watson ER
,
Lander GC
Discovery and Characterization of Novel BLIMP-1 Heterobifunctional Ligand-Directed Degraders.
Simmons BJ ,
Groocock L ,
Moreno J ,
Peters DS,
Hughes ME,
Veeravalli V,
Crawford JM,
Chalkley M,
Griffith M,
Plooster M,
Hu B,
Gamez J,
Leisten J,
Barnes MJ,
Chinn J,
Deb G,
Modi H,
Katepalli M,
Weiss D,
Won W,
Sun Z ,
Yu S,
Reid C,
Donnell AF ,
Li L,
Watson ER ,
Perrin-Ninkovic S,
Shi L ,
Narla RK,
Zapf CW,
Bence N,
Lopez-Girona A,
Riggs JR
(2025) J Med Chem , 68 , 25385 - 25402
,
Groocock L ,
Moreno J ,
Peters DS,
Hughes ME,
Veeravalli V,
Crawford JM,
Chalkley M,
Griffith M,
Plooster M,
Hu B,
Gamez J,
Leisten J,
Barnes MJ,
Chinn J,
Deb G,
Modi H,
Katepalli M,
Weiss D,
Won W,
Sun Z ,
Yu S,
Reid C,
Donnell AF ,
Li L,
Watson ER ,
Perrin-Ninkovic S,
Shi L ,
Narla RK,
Zapf CW,
Bence N,
Lopez-Girona A,
Riggs JR
(2025) J Med Chem , 68 , 25385 - 25402
Grant Support:
- Other private: (United States)