EMD-72140

Single-particle
3.18 Å
EMD-72140
3D View Gallery
Deposition: 14/08/2025
Map released: 26/08/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72140

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

HUWE1-USP7 local refinement, with focus on US7 catalytic domain

EMD-72140

Single-particle
3.18 Å
EMD-72140
3D View Gallery
Deposition: 14/08/2025
Map released: 26/08/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: HUWE1-USP7 complex

Deposition Authors: Yatskevich S, Juszkiewicz S
Molecular mechanism of HUWE1-HAPSTR1-USP7-mediated ubiquitin chain amplification on nuclear proteins.
Yatskevich S, Mohapatra J, Mroue R, Phu L, Leitner A, Azumaya CM, Vandlen R, Cheung TK, Soong TH, Rose CM, Ori A, Ciferri C, Juszkiewicz S
(2026) Mol Cell , 86 , 3803 - 3821.e17
PUBMED: 42753704
DOI: doi:10.1016/j.molcel.2026.08.016
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: