EMD-72119

Single-particle
3.3 Å
EMD-72119
3D View Gallery
Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72119

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9q18 summary report (pdf.gz) Map-9q18 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Class II ("T0D0") of Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dGpNHpp and DNA primer ending in TTAG

EMD-72119

Single-particle
3.3 Å
EMD-72119
3D View Gallery
Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Class II ("T0D0") of Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dGpNHpp and DNA primer ending in TTAG
Fitted models: 9q18

Deposition Authors: Wang Y, Liu B, He Y, Feigon J
Structures of human telomerase with BIBR1532 reveal novel mechanism of inhibition.
Wang Y, Liu B, He Y, Feigon J
(2026) Nat Chem Biol
PUBMED: 42230822
DOI: doi:10.1038/s41589-026-02238-6
ISSN: 1552-4469