EMD-72114

Single-particle
2.8 Å
EMD-72114
3D View Gallery
Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72114

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9q12 summary report (pdf.gz) Map-9q12 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human telomerase catalytic core with shelterin protein TPP1 and DNA primer ending in TTAG

EMD-72114

Single-particle
2.8 Å
EMD-72114
3D View Gallery
Deposition: 13/08/2025
Map released: 17/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human telomerase catalytic core with shelterin protein TPP1 and DNA primer ending in TTAG
Fitted models: 9q12

Deposition Authors: Wang Y, Liu B, He Y, Feigon J
Structures of human telomerase with BIBR1532 reveal novel mechanism of inhibition.
Wang Y, Liu B, He Y, Feigon J
(2026) Nat Chem Biol
PUBMED: 42230822
DOI: doi:10.1038/s41589-026-02238-6
ISSN: 1552-4469