EMD-72077

Single-particle
3.92 Å
EMD-72077
3D View Gallery
Deposition: 11/08/2025
Map released: 17/12/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72077
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9pzr summary report (pdf.gz) Map and 9pzr FULL report (pdf.gz)
EMICSS annotations (xml)

GluN1/GluN2A in complex with polyclonal autoantibody Fab fragments (class 2), glycine- and glutamate-bound state

EMD-72077

Single-particle
3.92 Å
EMD-72077
3D View Gallery
Deposition: 11/08/2025
Map released: 17/12/2025
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus, Mus musculus
Sample: GluN1/GluN2A in complex with polyclonal autoantibody Fab fragments (class 2), glycine- and glutamate-bound state
Fitted models: 9pzr

Deposition Authors: Kim J, Jalali-Yazdi F, Gouaux E
Cryo-EM of autoantibody-bound NMDA receptors reveals antigenic hotspots in an active immunization model of anti-NMDAR encephalitis.
Kim J, Jalali-Yazdi F, Jones BE, Westbrook GL, Gouaux E
(2026) Sci Adv , 12 , eaeb4249 - eaeb4249
PUBMED: 41533802
DOI: doi:10.1126/sciadv.aeb4249
ISSN: 2375-2548