EMD-71996

Single-particle
3.41 Å
EMD-71996
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Deposition: 06/08/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71996
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Unlatched-state loperamide-mu opioid receptor-Gi GDPbS complex (rebound) - Locally refined receptor map

EMD-71996

Single-particle
3.41 Å
EMD-71996
3D View Gallery
Deposition: 06/08/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Loperamide-mu opioid receptor in complex with Gai-GDPbS, Gb1 and Gg2

Deposition Authors: Gati C, Khan S, Han GW

Ligand efficacy is driven by conformational control of nucleotide exchange at the mu opioid receptor.
Khan S, Han GW, Gati C
To Be Published