EMD-71897

Helical reconstruction
2.3 Å
EMD-71897
3D View Gallery
Deposition: 04/08/2025
Map released: 18/03/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71897
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9pvz summary report (pdf.gz) Map and 9pvz FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of cardiac amyloid fibril from a variant apolipoprotein A-I R173P amyloidosis patient

EMD-71897

Helical reconstruction
2.3 Å
EMD-71897
3D View Gallery
Deposition: 04/08/2025
Map released: 18/03/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: amyloid fibrils of apoliprotein A-I amyloidosis, variant R173P from cardiac tissue
Fitted models: 9pvz

Deposition Authors: Nguyen BA , Saelices L
Cryo-EM reveals structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations.
Nguyen BA , Fernandez-Ramirez MDC, Bassett P, Singh V, Singh P, Pekala M, Villalon L, Ahmed Y, Lemoff A, Evers B, Lopez C, Kluve-Beckerman B, Saelices L
(2026) Nat Commun
PUBMED: 41991931
DOI: doi:10.1038/s41467-026-72150-z
ISSN: 2041-1723