EMD-71893

Single-particle
3.27 Å
EMD-71893
3D View Gallery
Deposition: 01/08/2025
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71893

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9pvm summary report (pdf.gz) Map-9pvm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

cryoEM structure of drug bound human SLC33A1 transporter

EMD-71893

Single-particle
3.27 Å
EMD-71893
3D View Gallery
Deposition: 01/08/2025
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Full length SLC33A1 with ligand bound
Fitted models: 9pvm

Deposition Authors: Rafiq M, Lander GC
Pharmacological Inhibition of SLC33A1 Promotes Endoplasmic Reticulum Hyperoxidation and Induces Adaptive IRE1/XBP1s Signaling.
Kutseikin S, Rafiq M, Bora P, Liu S, Homan RA, Mindrebo JT, Holcomb M, Petrassi HM, Qiu H, Redkina A, Sosna J, Lee TT, Hu X, Forli S, Parker CG, Lander GC, Birsoy K, Saez E, Wiseman RL
(2026) bioRxiv
PUBMED: 41757008
DOI: doi:10.64898/2026.02.17.706344
ISSN: 2692-8205