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EMD-71819
Cryo-EM structure of NCLX with calcium (class 3a)
EMD-71819
Single-particle2.6 Å
Deposition: 24/07/2025Map released: 10/09/2025
Last modified: 05/11/2025
Sample Organism:
Homo sapiens,
Rattus norvegicus
Sample: NCLX without Calcium
Fitted models: 9ps1
Deposition Authors: Zhang J
,
Feng L ,
Feng L
Sample: NCLX without Calcium
Fitted models: 9ps1
Deposition Authors: Zhang J
,
Feng L ,
Feng L
Structure and mechanism of the mitochondrial calcium transporter NCLX.
Fan M,
Tsai CW ,
Zhang J ,
Zhang J ,
Krishnan AR ,
Liu TY,
Huang YL,
Aydin D ,
Du S ,
Sobecks BL,
Rodriguez MX,
Reiter AH ,
Bertozzi CR ,
Dror RO ,
Tsai MF ,
Feng L
(2025) Nature , 646 , 1272 - 1280
,
Zhang J ,
Zhang J ,
Krishnan AR ,
Liu TY,
Huang YL,
Aydin D ,
Du S ,
Sobecks BL,
Rodriguez MX,
Reiter AH ,
Bertozzi CR ,
Dror RO ,
Tsai MF ,
Feng L
(2025) Nature , 646 , 1272 - 1280
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): (United States)
- The G. Harold and Leila Y. Mathers Foundation: (United States)