EMD-71783

Single-particle
3.29 Å
EMD-71783
3D View Gallery
Deposition: 22/07/2025
Map released: 20/08/2025
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71783
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9pqd summary report (pdf.gz) Map and 9pqd FULL report (pdf.gz)
EMICSS annotations (xml)

Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and compound Z7149

EMD-71783

Single-particle
3.29 Å
EMD-71783
3D View Gallery
Deposition: 22/07/2025
Map released: 20/08/2025
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and compound Z7149
Fitted models: 9pqd

Deposition Authors: Srinivasan K , Wu Y, Billesboelle C, Kim JY , Manglik A, Shoichet BK
Large Library Docking for Polypharmacology.
Wu Y, Vigneron S, Braz J, Srinivasan K , Fink EA , Huang XP, Xu X, Huebner H , Kim JY , Wang J , Pfeiffer T , Sakamoto K , Radchenko DS , Rodriguiz RM, Moroz YS , Irwin JJ, Gmeiner P , Billesboelle C, Roth BL , Basbaum AI, Manglik A, Wetsel WC, Shoichet BK
(2026) J Med Chem
PUBMED: 41712624
DOI: doi:10.1021/acs.jmedchem.5c03810
ISSN: 0022-2623
ASTM: JMCMAR