EMD-71770

Single-particle
3.4 Å
EMD-71770
3D View Gallery
Deposition: 21/07/2025
Map released: 04/03/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71770
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9pns summary report (pdf.gz) Map and 9pns FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human serotonin transporter bound to small molecule zPZd in lipid nanodisc and NaCl

EMD-71770

Single-particle
3.4 Å
EMD-71770
3D View Gallery
Deposition: 21/07/2025
Map released: 04/03/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Human serotonin transporter in complex with Fab15B8 bound to zPZd in NaCl
Fitted models: 9pns

Deposition Authors: Billesboelle CB, Manglik A
Large Library Docking for Polypharmacology.
Wu Y, Vigneron S, Braz J, Srinivasan K , Fink EA , Huang XP, Xu X, Huebner H , Kim JY , Wang J , Pfeiffer T , Sakamoto K , Radchenko DS , Rodriguiz RM, Moroz YS , Irwin JJ, Gmeiner P , Billesboelle C, Roth BL , Basbaum AI, Manglik A, Wetsel WC, Shoichet BK
(2026) J Med Chem
PUBMED: 41712624
DOI: doi:10.1021/acs.jmedchem.5c03810
ISSN: 0022-2623
ASTM: JMCMAR