EMD-71586

Single-particle
8.45 Å
EMD-71586
3D View Gallery
Deposition: 03/07/2025
Map released: 24/12/2025
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71586
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EMICSS annotations (xml)

Negative stain EM map of EBV glycoprotein gH/gL in complex with glycoprotein gp42 and FAB ATX-42-2 Open conformation

EMD-71586

Single-particle
8.45 Å
EMD-71586
3D View Gallery
Deposition: 03/07/2025
Map released: 24/12/2025
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: human gammaherpesvirus 4, Mus musculus
Sample: Coexpressed EBV surface glycoprotein gH/gL complex 1:1 with glucoprotein gp42 and then 1:1 with FAB ATX-42-2

Deposition Authors: Lang K , Kher G , Chan CB , Pancera M
Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development.
Chhan CB, Lang K , Davis AR, Wan YH, Aldridge NT, Kher G , Scharffenberger SC, Hardy SR, Iureniev R, Giltiay NV, Edwards KR, Radtke S, Kiem HP, Pancera M , McGuire AT
(2026) Cell Rep Med , 7 , 102618 - 102618
PUBMED: 41707657
DOI: doi:10.1016/j.xcrm.2026.102618
ISSN: 2666-3791