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EMD-71531

Single-particle
3.2 Å
EMD-71531 Deposition: 30/06/2025
Map released: 15/10/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71531

Angiopoietin-2 in complex with engineered conformationally rigid Fab 5A12.6DS, used for comparison with Fab 5A12.WT

EMD-71531

Single-particle
3.2 Å
EMD-71531 Deposition: 30/06/2025
Map released: 15/10/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ang2:6DS Fab

Deposition Authors: Kung J , Johnson MC , Tegunov D , Jao CC, Wu P, Oh A, Lin M, Daria JM, Koth CM , Arthur CP, Rohou A , Sudhamsu J
Disulfide-constrained Fabs overcome target size limitation for high-resolution single particle cryoEM.
Kung JE, Johnson MC , Tegunov D , Jao CC, Wu P, Oh A, Lin M, Daria JM, Koth CM , Arthur CP, Rohou A , Sudhamsu J
(2025) Nat Commun , 16 , 8687 - 8687
PUBMED: 41027970
DOI: doi:10.1038/s41467-025-63766-8
ISSN: 2041-1723
Grant Support: