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EMD-71531
Angiopoietin-2 in complex with engineered conformationally rigid Fab 5A12.6DS, used for comparison with Fab 5A12.WT
EMD-71531
Single-particle3.2 Å
Deposition: 30/06/2025Map released: 15/10/2025
Last modified: 15/10/2025
Sample Organism:
Homo sapiens
Sample: Ang2:6DS Fab
Deposition Authors: Kung J
,
Johnson MC
,
Tegunov D
,
Jao CC,
Wu P,
Oh A,
Lin M,
Daria JM,
Koth CM
,
Arthur CP,
Rohou A
,
Sudhamsu J
Sample: Ang2:6DS Fab
Deposition Authors: Kung J
,
Johnson MC
,
Tegunov D
,
Jao CC,
Wu P,
Oh A,
Lin M,
Daria JM,
Koth CM
,
Arthur CP,
Rohou A
,
Sudhamsu J
Disulfide-constrained Fabs overcome target size limitation for high-resolution single particle cryoEM.
Kung JE,
Johnson MC
,
Tegunov D
,
Jao CC,
Wu P,
Oh A,
Lin M,
Daria JM,
Koth CM
,
Arthur CP,
Rohou A
,
Sudhamsu J
(2025) Nat Commun , 16 , 8687 - 8687
,
Tegunov D
,
Jao CC,
Wu P,
Oh A,
Lin M,
Daria JM,
Koth CM
,
Arthur CP,
Rohou A
,
Sudhamsu J
(2025) Nat Commun , 16 , 8687 - 8687
Grant Support:
