EMD-71288

Single-particle
2.76 Å
EMD-71288
3D View Gallery
Deposition: 17/06/2025
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71288

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9p4x summary report (pdf.gz) Map-9p4x FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human EAAT3 with compound 3e and cholesterol bound at inward facing state

EMD-71288

Single-particle
2.76 Å
EMD-71288
3D View Gallery
Deposition: 17/06/2025
Map released: 30/07/2025
Last modified: 30/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human excitatory amino acid transporter 3
Fitted models: 9p4x

Deposition Authors: Qiu B , Boudker O
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer.
Koochaki P, Qiu B , Coker JA, Earsley A, Wang NS, Romigh T, Goins CM, Stauffer SR, Boudker O, Chakraborty AA
(2025) bioRxiv
PUBMED: 40672197
DOI: doi:10.1101/2025.07.03.663021
ISSN: 2692-8205
Grant Support: