EMD-71249

Single-particle
3.3 Å
EMD-71249
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Deposition: 14/06/2025
Map released: 07/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71249
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Zebrafish TRPM5 with 2uM Ca in GDN detergent

EMD-71249

Single-particle
3.3 Å
EMD-71249
3D View Gallery
Deposition: 14/06/2025
Map released: 07/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Danio rerio
Sample: zebrafish TRPM5 in GDN detergent with 2uM calcium

Deposition Authors: Ruan Z, Du J, Lu W
A single allosteric site merges activation, modulation and inhibition in TRPM5.
Ruan Z, Lee J, Li Y, Orozco IJ, Du J, Lu W
(2026) Nat Chem Biol
PUBMED: 41491833
DOI: doi:10.1038/s41589-025-02097-7
ISSN: 1552-4469