EMDB EMD-7090

Single particle reconstruction
6.5Å resolution

Cryo-EM structure of human insulin degrading enzyme

Map released:
Last modified:
Overview of EMD-7090
Source organism: Homo sapiens [9606]
Fitted atomic model: 6bf6
Related EM entries by publication: EMD-7041, EMD-7062, EMD-7065, EMD-7066, EMD-7091, EMD-7092, EMD-7093
Primary publication:
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
Elife 7 - (2018)
PMID: 29596046

Function and Biology Details

Sample name: Insulin degrading enzyme
Proteins: Insulin degrading enzyme, Insulin-degrading enzyme

Experimental Information Details

Resolution: 6.5Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 (4k x 4k)