EMD-70722
TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
EMD-70722
Single-particle3.2 Å
Deposition: 19/05/2025Map released: 13/05/2026
Last modified: 03/06/2026
Sample Organism:
Homo sapiens,
Lama glama
Sample: TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Fitted models: 9opr
Deposition Authors: McCallum M
,
Seattle Structural Genomics Center for Infectious Disease (SSGCID),
Veesler D
Sample: TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Fitted models: 9opr
Deposition Authors: McCallum M
,
Seattle Structural Genomics Center for Infectious Disease (SSGCID),
Veesler D
TMPRSS2-mediated coronavirus spike activation and inhibition.
McCallum M ,
Case JB ,
Brown JT,
Park YJ ,
Lee J,
Sutherland E ,
Aggarwal A,
Gibson C,
Lempp FA ,
Stewart C ,
Tortorici MA ,
Sanapala S,
Low JS,
Asarnow D ,
Bohan D ,
Dellota Jr E,
Merz B,
Chawla B,
Kar S,
Lanzavecchia A ,
Sallusto F,
Riley NM ,
Turville S,
Purcell L,
Diamond MS ,
Veesler D
(2026) Nat Struct Mol Biol , 33 , 810 - 823
,
Case JB ,
Brown JT,
Park YJ ,
Lee J,
Sutherland E ,
Aggarwal A,
Gibson C,
Lempp FA ,
Stewart C ,
Tortorici MA ,
Sanapala S,
Low JS,
Asarnow D ,
Bohan D ,
Dellota Jr E,
Merz B,
Chawla B,
Kar S,
Lanzavecchia A ,
Sallusto F,
Riley NM ,
Turville S,
Purcell L,
Diamond MS ,
Veesler D
(2026) Nat Struct Mol Biol , 33 , 810 - 823
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)